Osteosarcoma of the jaws: a review of literature and a case report on synchronous multicentric osteosarcomasReport as inadecuate




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World Journal of Surgical Oncology

, 10:240

First Online: 12 November 2012Received: 24 October 2011Accepted: 19 September 2012

Abstract

BackgroundIn the head and neck region, osteosarcoma is the most common primary malignant bone tumor, representing 23% of total head and neck malignancies. Osteosarcomas of the jaws are nevertheless rare lesions, representing only 2 to 10% of all osteosarcomas. This report reviews a single-center histopathology experience with craniofacial osteosarcomas, and reports the management of unusually large synchronous mandibular and maxillary osteosarcomas in a patient.

Patients and methodsA search of the hospital pathology database for specimens with a histological diagnosis of osteosarcomas submitted between July 1992 and May 2011 was made. A chart review of a patient with large synchronous maxillary and mandibular osteosarcomas was performed, and is reported.

Case presentationA 21-year-old African man with large maxillary and mandibular tumors under palliative care presented with increasing difficulties with eating, speech, and breathing. Surgical debulking was performed, with histology confirming synchronous osteosarcomas of the mandible and maxilla. The patient is well after one year, with no evidence of recurrence, having undergone no further treatment.

ConclusionOsteosarcomas of the jaw remain enigmatic, and a number of difficulties related to their diagnosis and treatment are yet to be resolved. True synchronous multicentric osteosarcomas of the jaws are extremely rare but, like other osteosarcomas of the jaws, have a favorable outcome, and palliative resection of such lesions, though challenging, can therefore lead to an enormously improved quality of life and self-image, and may even offer the opportunity for cure.

KeywordsJaw osteosarcomas Multicentric Palliative surgery Synchronous AbbreviationsCTcomputed tomography.

Electronic supplementary materialThe online version of this article doi:10.1186-1477-7819-10-240 contains supplementary material, which is available to authorized users.

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Author: Peter M Nthumba

Source: https://link.springer.com/



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