Modern surgical management of tongue carcinoma - A clinical retrospective research over a 12 years periodReport as inadecuate




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Head and Neck Oncology

, 3:43

First Online: 29 September 2011Received: 18 September 2011Accepted: 29 September 2011

Abstract

ObjectivesIn this retrospective study, we present a clinical review of our experience with tongue cancer in order to obtain valid criteria for therapeutic decision-making.

Materials and methodsBetween August 1999 and June 2011, a total of 398 patients with squamous cell carcinoma of the tongue were treated at the Department of Oral and Maxillofacial Surgery, King Edward Medical University Lahore Pakistan. Data concerning patient characteristics, clinical and pathologic tumour characteristics and treatment strategies and their results were obtained from a retrospective review of medical records. The average follow-up was 4.6 years. Statistical analysis for survival was calculated by the method of Kaplan and Meier.

ResultsThere were 398 total patients. The mean age at diagnosis was 49.5 years,. 224 56.3% were male and 174 43.7% female male-female ratio = 1.3:1.332-398 patients received surgical treatment, whereas 66 patients were excluded from surgical treatment and received primary radio chemo therapy after biopsy. Tongue carcinoma patients treated by non surgical treatment modalities had 5 years survival rate of 45.5% and patients with surgical intervention had survival rate of 96.1%.

ConclusionsWe recommend categorical bilateral neck dissection in order to reliably remove occult lymph node metastases. Adjuvant treatment modalities should be applied more frequently in controlled clinical trials and should generally be implemented in cases with unclear margins and lymphatic spread.

Clinical relevanceThis study provides modern treatment strategies for the tongue carcinoma.

Keywordstongue cancer squamous cell carcinoma resection survival prognostic factors Electronic supplementary materialThe online version of this article doi:10.1186-1758-3284-3-43 contains supplementary material, which is available to authorized users.

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Author: Majeed Rana - Asifa Iqbal - Riaz Warraich - Martin Ruecker - André M Eckardt - Nils-Claudius Gellrich

Source: https://link.springer.com/







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