Accuracy of a Novel Non-Invasive technology based EZSCAN system for the diagnosis of diabetes mellitus in ChineseReport as inadecuate




Accuracy of a Novel Non-Invasive technology based EZSCAN system for the diagnosis of diabetes mellitus in Chinese - Download this document for free, or read online. Document in PDF available to download.

Diabetology and Metabolic Syndrome

, 3:36

First Online: 22 December 2011Received: 25 July 2011Accepted: 22 December 2011

Abstract

BackgroundA new simple technique based on iontophoresis technology EZSCAN, Impeto Medical, Paris, France has recently been developed for the screening of diabetes. In the present study, we investigated the accuracy of this system for the diagnosis of diabetes mellitus in Chinese.

MethodsWe performed the EZSCAN test in diabetic and non-diabetic subjects. EZSCAN measures electrochemical conductance EC at forehead, hands and feet, and derives a diabetes index with a value ranging from 0 to 100. Diabetes mellitus was defined as a plasma glucose concentration of at least 7 mmol-l at fasting or 11.1 mmol-l at 2 hours after glucose load, or as the use of antidiabetic drugs.

ResultsThe 195 study participants 51% men, mean age 52 years included 75 diabetic patients use of antidiabetic drugs 81% and 120 non-diabetic subjects. EC micro Siemens, μSi was significantly P < 0.001 lower in diabetic patients at the hands 44 vs. 61 and feet 51 vs. 69 locations, but not at the forehead 15 vs. 17, P = 0.39. When a diabetes index of 40 suggested by the manufacturer was used as the threshold, the sensitivity and specificity for the diagnosis of diabetes mellitus was 85% and 64%, respectively. In 80 patients who underwent an oral glucose tolerance test, EC at hands and feet and the diabetes index were significantly P < 0.001 associated with both 2-hour post-load plasma glucose and serum glycosylated haemoglobin.

ConclusionsEZSCAN might be useful in screening diabetes mellitus with reasonable sensitivity and specificity.

KeywordsEZSCAN Diabetes mellitus Iontophoresis technology Electronic supplementary materialThe online version of this article doi:10.1186-1758-5996-3-36 contains supplementary material, which is available to authorized users.

Download fulltext PDF



Author: Chang-Sheng Sheng - Wei-Fang Zeng - Qi-Fang Huang - Jean-Paul Deslypere - Yan Li - Ji-Guang Wang

Source: https://link.springer.com/







Related documents