HPV prevalence and type distribution in women with or without cervical lesions in the Northeast region of RomaniaReport as inadecuate




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Virology Journal

, 8:558

First Online: 22 December 2011Received: 28 July 2011Accepted: 22 December 2011

Abstract

BackgroundCervical cancer is a major public health problem worldwide. While Romania has the highest incidence of cervical cancer in Europe, the prevalence of HPV has not been evaluated. We report the first data on HPV prevalence and type distribution in Northeast Romania.

MethodsHPV prevalence and genotype distribution was investigated in 514 consecutively women with or without cervical lesions in Northeast Romania. Genotyping was performed with Linear Array Genotyping-Roche kit.

ResultsIn our study group, 192-514 37.4% patients were positive for HPV infected with single and with multiple HPV types. Most frequent types were: 16 10.5%, 53 5.44%, 51 5.05%, 52 4.08% 18 2.91% and 31 2.73%.

ConclusionsInfection with high risk types of HPV is common in Northeast Romania. Enhanced and systematic screening for cervical cancer is needed. Our results call for the implementation of a National HPV vaccine program in Romania.

KeywordsHPV Screening Cytology Prevalence Persistence Vaccination List of abbreviationsHPVHuman papilloma virus

HR HPV typesHigh Risk HPV types

pHR HPVProbably high risk HPV types

LR HPV typesLow risk HPV types.

Electronic supplementary materialThe online version of this article doi:10.1186-1743-422X-8-558 contains supplementary material, which is available to authorized users.

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Author: Ramona Gabriela Ursu - Mircea Onofriescu - Dragoş Nemescu - Luminiţa-Smaranda Iancu

Source: https://link.springer.com/



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