Macular hole formation, progression, and surgical repair: case series of serial optical coherence tomography and time lapse morphing video studyReport as inadecuate




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BMC Ophthalmology

, 10:24

First Online: 17 September 2010Received: 06 April 2010Accepted: 17 September 2010

Abstract

BackgroundTo use a new medium to dynamically visualize serial optical coherence tomography OCT scans in order to illustrate and elucidate the pathogenesis of idiopathic macular hole formation, progression, and surgical closure.

Case PresentationsTwo patients at the onset of symptoms with early stage macular holes and one patient following repair were followed with serial OCTs. Images centered at the fovea and at the same orientation were digitally exported and morphed into an Audiovisual Interleaving avi movie format. Morphing videos from serial OCTs allowed the OCTs to be viewed dynamically. The videos supported anterior-posterior vitreofoveal traction as the initial event in macular hole formation. Progression of the macular hole occurred with increased cystic thickening of the fovea without evidence of further vitreofoveal traction. During cyst formation, the macular hole enlarged as the edges of the hole became elevated from the retinal pigment epithelium RPE with an increase in subretinal fluid. Surgical repair of a macular hole revealed initial closure of the macular hole with subsequent reabsorption of the sub-retinal fluid and restoration of the foveal contour.

ConclusionsMorphing videos from serial OCTs are a useful tool and helped illustrate and support anterior-posterior vitreofoveal traction with subsequent retinal hydration as the pathogenesis of idiopathic macular holes.

Electronic supplementary materialThe online version of this article doi:10.1186-1471-2415-10-24 contains supplementary material, which is available to authorized users.

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Author: Ronald C Gentile - Gennady Landa - Mauricio E Pons - Dean Eliott - Richard B Rosen

Source: https://link.springer.com/







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